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Manus Aktteva Biopharma LLP offers Bivalirudin, 128270-60-0, for RND and its crude form for your evaluation requirements with supportive technical package required for evaluation.
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Bivalirudin
Bivalirudin
Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin.1,3,5 It inhibits both circulating and clot-bound thrombin5>, while also inhibiting thrombin-mediated platelet activation and aggregation6. Bivalirudin has a quick onset of action and a short half-life.1 It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS).1 It does not require a binding cofactor such as antithrombin and does not activate platelets.3,4 These characteristics make bivalirudin an ideal alternative to heparin. Manus Aktteva Biopharma LLP offers Bivalirudin, 128270-60-0, for RND and its crude form for your evaluation requirements with supportive technical package required for evaluation.
Product Reference ID: MA-GA-551-O
Bivalirudin, 128270-60-0
Chemical Name: D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
Description
CAS number 128270-60-0
Synonym Bivalirudin, (15S,21S,24S,27S,30S) - 15 - (2-amino-2-oxoethyl) - 1 - [(2S)-1-{(2S)-2-[({(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl} carbonyl)amino]-5-carbamimidamidopentanoyl}pyrrolidin-2-yl] - 24 - benzyl-30-({(2S,3S)-1-[(2S)-2 -{[(2S)-4-carboxy - 1 - {[(2S)-4-carboxy-1-{[(2S)-1-{[(1S)-1-carboxy-3-methylbutyl]amino}-3 -(4-hydroxyphenyl) - 1 - oxopropan-2-yl]amino} - 1 - oxobutan-2-yl]amino}-1-oxobutan-2-yl]carbamoyl}pyrroli\ndin -1-yl]-3-methyl - 1 - oxopentan-2-yl}carbamoyl) - 27 - (2-carboxyethyl) - 21 - (carboxymethyl) - 1,4,7,10,13,16,19,22, 25,28 - decaoxo -2,5,8,11,14,17,20,23,26,29 -decaazatritriacontan-33-oic acid
Molecular Formula C98H138N24O33
Molecular Weight 2180.29
Specifications Purity(HPLC)=99%; White or almost white powder
Packing Export worthy packing
Material Safety Data Sheet
Available on request
Availability RND & Evaluation
Drug Master File Can be made available
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